Leaders:

Oliver Stegle (Heidelberg), Ivo Buchhalter (Heidelberg), and Patrick Kemmeren (Utrecht)

Abstract:

WP2 is responsible for designing a secure, federated long-term data storage solution for genomic data that allows for remote execution of pipelines developed in WP3 while still complying with international legal and ethical requirements.

Tasks:

• Harmonization of genetic data repositories following the principles of the European Genome-Phenome Archive that will result in a federation of data repositories for the purpose of the international pediatric cancer portal (PedCan) that comply with national laws
• Connecting participating federated data repositories making use of authentication and authorization services to ensure secure access
• Implementation of minimal metadata standards to ensure minimal clinical and sequencing annotations are provided with the raw data; also that data is FAIR and standardized through ontologies
• Provide infrastructure for WP3 bioinformatics pipelines to retrieve raw and processed data in an automated fashion