AIMS AND FEATURES
- Real-time federated archiving of raw data
- Harmonization of data dictionaries for molecular & clinical data
- Harmonization of omics pipelines for a core processed dataset
- Data visualization and sharing
- Coordinate a parallel track of overarching scientific analyses
- Involve patient representatives, ethical and legal expertise at all stages
MOLECULAR DIAGNOSIS FOR TARGETED THERAPY
- Molecular profiling of high risk and relapsed disease
- Average time between sample receipt and initial reporting of 4 weeks
- Molecular findings are included into clinical decision making
- Demonstrated value of the molecular diagnostic platform
GENERAL CLINICAL PROGRAM OVERVIEW
For each individual patient for whom no established therapy is currently available, a molecular profile of the tumor (and tumor microenvironment) should be established in order to identify potentially suitable drugs in a personalized manner. Our clinical programs recruit patients and utilize modern sequencing technologies to identify potential targets and biomarkers. Further discussion among disease experts (known as tumor boards) prioritizes the identified targets for which a candidate therapeutic drug is available resulting in a personalized treatment recommendation.
ITCC ORGANIZATIONAL STRUCTURE
The consortium comprises several subgroups working on specific tasks which provides the framework to integrate the diverse and complementary expertise required to successfully implement and complete such a complex project. The data portal initiative is kindly supported by the Dietmar Hopp foundation.